Determination of Cyanide in Biological and Non - Biological Matrices by Headspace Gas Chromatography Coupled to Flame - Ionization Detector

Determination of Triethylamine, Pyridine and Dimethyl Formamide Content in Telmisartan by Headspace Gas Chromatography Using Flame Ionization Detector

Determination of Residual Epichlorohydrin in Sevelamer Hydrochloride by Static Headspace Gas Chromatography with Flame Ionization Detection

A sensitive static headspace gas chromatographic method was developed and validated for the determination of residual epichlorohydrin (ECH) in sevelamer hydrochloride (SVH) drug substance. This method utilized a Phenomenex Zebron ZB-WAX GC column, helium as carrier gas with flame ionization detection. The critical experimental parameters, such as, headspace vial incubation time and incubation t...

Effect of using Propanol as internal standard on quantitative determination of ethanol in different biological matrices by head space-Gas Chromatography-Flame Ionization Detector

Identification and quantification of ethanol in biological samples such as blood and urine is of paramount importance in forensic toxicological laboratories. Despite of the fact that there are several methods are available for quantification of ethanol in forensic samples, an accurate quantification with minimum standard deviation is still a challenging task in forensic toxicological laboratori...

Determination of Synthetic Phenolic Antioxidants in Biological Fluids Based on Air-assisted Liquid-liquid Microextraction Followed by Gas Chromatography-flame Ionization Detection

An air–assisted liquid–liquid microextraction method for the extraction and preconcentration of trace amounts of some synthetic phenolic antioxidants in biological fluids followed by their determination by gas chromatography–flame ionization detection has been reported. In this method the target analytes are extracted into a few microliters of carbon tetrachloride (extraction solvent) from an a...

Residual solvent determination by head space gas chromatography with flame ionization detector in omeprazole API

Residual solvents in pharmaceutical samples are monitored using gas chromatography with head space. Based on good manufacturing practices, measuring residual solvents is mandatory for the release testing of all active pharmaceutical ingredients (API). The analysis of residual organic solvents (methanol, acetone, cyclohexane, dichloromethane, toluene) in Omeprazole, an active pharmaceutical ingr...